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Triclabendazole is an antiparasitic medication primarily used to treat liver fluke infections, especially Fasciola hepatica and Fasciola gigantica. Because these parasites live and migrate within the liver and bile ducts, triclabendazole’s effects are closely linked to liver function.

After oral administration, triclabendazole is absorbed in the intestine and extensively metabolized in the liver. It is converted into active metabolites—triclabendazole sulfoxide and sulfone—which are responsible for killing both immature and adult liver flukes. These metabolites concentrate in bile, allowing the drug to directly target parasites residing in the biliary system. This targeted action makes triclabendazole highly effective in clearing liver fluke infections. Triclabendazole Buy Online at best pharmacy Medzsupplier.

In most patients, triclabendazole is well tolerated by the liver. However, temporary changes in liver enzyme levels may occur during or shortly after treatment. Mild elevations in enzymes such as ALT, AST, or alkaline phosphatase are usually short-lived and often reflect the liver’s response to dying parasites rather than direct drug toxicity. As the flukes are destroyed, inflammation in the bile ducts can temporarily increase, leading to abdominal pain, nausea, or mild jaundice in some cases.

Serious liver injury due to triclabendazole is rare. Patients with heavy parasite loads or pre-existing liver disease may experience more noticeable symptoms, so liver function monitoring is often recommended before and after treatment in such individuals. In the majority of cases, liver enzyme levels return to normal once the infection resolves.

Overall, triclabendazole supports liver recovery by eliminating parasites that cause chronic inflammation, bile duct obstruction, and long-term liver damage. When used under medical supervision and at recommended doses, its benefits in restoring liver health far outweigh the risk of temporary liver-related side effects.